How much is a ticket from Panama City to Santa Cruz de la Sierra?

Depending on when you travel and how far in advance you book, fares between Panama City and Santa Cruz can differ a lot.

Choose a date to explore the best fares now.

If you’re flexible with timing, consider overnight flights — they often cost less and are less crowded. Exploring multiple date and time combinations can help you find the cheapest solution.

Exploring all airports near Panama City and Santa Cruz

Checking all the airports available in the area can give you more departure and arrival options for your trip.

• Airports in Panama City: 2 different airports operate in Panama City - Pacífico International Airport, Paitilla.
• Airports in Santa Cruz: Try also checking Santa Cruz along with Santa Cruz - Viru Viru.

Looking at expected traffic to the airport can help avoid surprises on departure day. On busy routes, flying from a quieter airport might also save you money.

Customize your flight from Panama City to Santa Cruz de la Sierra

Jetcost allows you to filter by travel dates, duration, layovers, carriers, and booking providers. You’ll find direct and connecting flights, one-way or round-trip, from the best airlines and travel agencies.

Other popular destinations

Thinking about Bolivia? You might also consider: Cochabamba, La Paz, Santa Cruz, Sucre, Tarija.

You can sort results by price, duration, or departure time to find the best option for you. When available, results always include both low-cost and traditional airlines.